By Brian K. Hall
Bones and Cartilage presents the main in-depth assessment and synthesis assembled at the subject, throughout all vertebrates. It examines the functionality, improvement and evolution of bone and cartilage as tissues, organs and skeletal platforms. It describes how bone and cartilage improve in embryos and are maintained in adults, how bone is repaired once we holiday a leg, or regenerates while a newt grows a brand new limb, or a lizard a brand new tail.
The moment version of Bones and Cartilage comprises the newest wisdom of molecular, mobile, developmental and evolutionary tactics, that are built-in to stipulate a unified self-discipline of developmental and evolutionary skeletal biology. also, assurance contains how the molecular and mobile facets of bones and cartilage range in numerous skeletal platforms and throughout species, besides the most recent experiences and hypotheses of relationships among skeletal cells and the newest info on coupling among osteocytes and osteoclasts All chapters were revised and up to date to incorporate the most recent learn.
- Offers whole insurance of each element of bone and cartilage, with up to date references and broad illustrations
- Integrates improvement and evolution of the skeleton, besides a synthesis of differentiation, development and patterning
- Treats all degrees from molecular to medical, embryos to evolution, and covers all vertebrates in addition to invertebrate cartilages
- Includes new chapters on evolutionary skeletal biology that spotlight basic version and variability, and edition outdoor the norm (neomorphs, atavisms)
- Updates hypotheses at the origination of cartilage utilizing new phylogenetic, mobile and genetic data
- Covers stem cells in embryos and adults, together with mesenchymal stem cells and their use in genetic engineering of cartilage, and the concept that of the stem mobilephone niche
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Additional resources for Bones and Cartilage. Developmental and Evolutionary Skeletal Biology
A highly sophisticated knowledge of the microenvironment in which bone and bones develop is required before we can interpret this diversity of expression of the differentiated state of osteocytes. One of the aims of the book is to marshal and analyse some of that evidence. Osteones can be detected in ground sections of fossilized bone. A histological analysis of tibiae from an early bird was used by Houde (1987) to argue that Hesperornis had osteones similar to those of most living (neognathous) birds.
The form of neurofibromatosis from which Joseph Merrick – the ‘elephant man’ – was thought to have suffered, was named von Recklinghausen neurofibromatosis after Friedrich Daniel von Recklinghausen (1833–1910), who attracted postgraduate students from all over the world, but rarely bothered even to speak to them; see Hall and Hörstadius (1988) and Hall (1999a) for some details. 6. See H. M. Smith (1947), Ørvig (1967), Gardner (1971), Hancox (1972a), Pritchard (1972a), Ham (1974), Patterson (1977), Ham and Cormack (1979) and Smith and Hall (1990, 1993) for in-depth discussions of bone type and bone development from the perspectives of histologists, palaeontologists and Bone 7.
3, and see Ekanayake and Hall (1997) for details. (Fig. 10). Poole and his colleagues have demonstrated that: ● ● ● ● ● ● pericellular capsules of fine fibrils characterize deep but not superficial canine tibial articular cartilage; adult human articular cartilage contains similar chondrones; chondrones can be physically isolated as intact structural units; chondrones are rich in proteoglycans (Fig. 4 CARTILAGE GROWTH In contrast to the solely appositional growth of bone, cartilage growth is both internal (interstitial) by chondroblast/ cyte proliferation and deposition of ECM and appositional by addition to cartilage surfaces.